A statue of Asclepius. The Glypotek, Copenhagen.

Image via Wiki­pe­dia

Dear All,

I have been work­ing on this one for some time.

You can think of the spec­trum from patho­physiology to dis­ease to symp­to­mat­o­logy to be roughly as follows:

Root causes
Patho­physiology
Organ-specific dis­ease
Signs
Symp­toms

(As if lay­ers on a cake)

We often con­cen­trate, in clin­ical medi­cine on a small selec­tion of these, often closer to the bot­tom. How­ever, a lot of things are both easier to remem­ber and make more sense when clustered into related and over­lap­ping top­ics, or seen in terms of multi-organ disease.

A small hand­book that gives a con­cise, visual ref­er­ence would be helpful.

Ideally, it would be nice to have a com­pu­ta­tional bio­lo­gist involved in order to define accur­ate (and often start­ling) rela­tion­ships between vari­ous con­di­tions– (to take a banal example, smoking is an inde­pend­ent risk factor for devel­op­ing dia­betes).

Yours,

Deutschy, organ­ic­ally devel­op­ing our rail network!

Enhanced by Zemanta

One Response to A text­book of sys­temic disease

  1. thread says:

    I can see applic­a­tions of my AI course here (and I think AI is put to ser­i­ous work in the field already).

    The first 10 “chapters” (lec­ture groups) have been about inter­pret­ing prob­ab­il­it­ies with incom­plete observ­ab­il­ity (eg, determ­in­ing the cause of an event that has more than one pos­sible cause) and learn­ing from what obser­va­tions exist.

    Also, your “storylines” box is interesting.

Leave a Reply